Stereoselectivities of up to 98% have been found in the enzymic synthesis of b-hydroxy sulfoxides catalyzed by cyclohexanone monooxygenase (CHMO). The diastereoselectivity of the "one-pot" prepn. of the title compds. in the presence of bovine serum albumin has also been investigated.

Diastereoselective synthesis of beta-hydroxy sulfoxides: enzymatic and biomimetic approaches / S. Colonna, V. Pironti, F. Zambianchi, G. Ottolina, N. Gaggero, G. Celentano. - In: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. - ISSN 1434-193X. - 2007:2(2007), pp. 363-368. [10.1002/ejoc.200600624]

Diastereoselective synthesis of beta-hydroxy sulfoxides: enzymatic and biomimetic approaches

S. Colonna
;
V. Pironti
Secondo
;
N. Gaggero
Penultimo
;
G. Celentano
Ultimo
2007

Abstract

Stereoselectivities of up to 98% have been found in the enzymic synthesis of b-hydroxy sulfoxides catalyzed by cyclohexanone monooxygenase (CHMO). The diastereoselectivity of the "one-pot" prepn. of the title compds. in the presence of bovine serum albumin has also been investigated.
sulfoxides; cyclohexanone monooxygenase; kinetic resolution; bovine serum albumin; enzyme catalysis; asymmetric oxidation
Settore CHIM/06 - Chimica Organica
27-ott-2006
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/37823
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