Data on daptomycin use in the pediatric setting are scanty. We conducted a multicenter, retrospective study on 46 children treated with intravenous daptomycin at a mean dosage of 7.0 mg/kg/day and for a median of 14 days. Three children had adverse events possibly related to daptomycin. The drug was overall well tolerated, even with prolonged treatment.
Daptomycin for children in clinical practice experience / S. Garazzino, E. Castagnola, M. Di Gangi, R. Ortolano, A. Krzysztofiak, A. Nocerino, S. Esposito, P. D'Argenio, L. Galli, G. Losurdo, C. Calitri, P. Tovo, R. Bandettini, S. Giordano, P. Dones, O. Ziino, C. Mosa, M. Robazza, C. Tagliabue, L. Lancella, F. Carraro. - In: THE PEDIATRIC INFECTIOUS DISEASE JOURNAL. - ISSN 0891-3668. - 35:6(2016 Feb 23), pp. 639-641. [10.1097/INF.0000000000001121]
Daptomycin for children in clinical practice experience
S. Esposito;C. Tagliabue;
2016
Abstract
Data on daptomycin use in the pediatric setting are scanty. We conducted a multicenter, retrospective study on 46 children treated with intravenous daptomycin at a mean dosage of 7.0 mg/kg/day and for a median of 14 days. Three children had adverse events possibly related to daptomycin. The drug was overall well tolerated, even with prolonged treatment.
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