The catalytic enantioselective addition of allyltributylstannane to N-protected greek small letter alpha-iminoesters promoted by silver(I) trifluoromethanesulfonate in the presence of chiral imine ligands was studied. After testing several chiral imines derived from 1,2-diaminocyclohexane and binaphthyl diamine a very simple experimental procedure was developed that allowed us to obtain optically active homoallylic amines in very high yields and enantioselectivities up to 71%.
Catalytic, enantioselective allylation of alfa-iminoesters promoted by Silver(I) complexes of chiral imines / F. Colombo, R. Annunziata, M. Benaglia. - In: TETRAHEDRON LETTERS. - ISSN 0040-4039. - 48:15(2007), pp. 2687-2690.
Titolo: | Catalytic, enantioselective allylation of alfa-iminoesters promoted by Silver(I) complexes of chiral imines |
Autori: | COLOMBO, FEDERICA (Primo) ANNUNZIATA, RITA MARIA (Secondo) BENAGLIA, MAURIZIO (Ultimo) |
Parole Chiave: | Chiral catalysts; Chiral imines; Enantioselective catalysis; Homoallylic amines; Silver complex |
Settore Scientifico Disciplinare: | Settore CHIM/06 - Chimica Organica |
Data di pubblicazione: | 2007 |
Rivista: | |
Sostituisce: | http://hdl.handle.net/2434/36205 |
Tipologia: | Article (author) |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1016/j.tetlet.2007.02.071 |
Appare nelle tipologie: | 01 - Articolo su periodico |