The catalytic enantioselective addition of allyltributylstannane to N-protected greek small letter alpha-iminoesters promoted by silver(I) trifluoromethanesulfonate in the presence of chiral imine ligands was studied. After testing several chiral imines derived from 1,2-diaminocyclohexane and binaphthyl diamine a very simple experimental procedure was developed that allowed us to obtain optically active homoallylic amines in very high yields and enantioselectivities up to 71%.

Catalytic, enantioselective allylation of alfa-iminoesters promoted by Silver(I) complexes of chiral imines / F. Colombo, R. Annunziata, M. Benaglia. - In: TETRAHEDRON LETTERS. - ISSN 0040-4039. - 48:15(2007), pp. 2687-2690. [10.1016/j.tetlet.2007.02.071]

Catalytic, enantioselective allylation of alfa-iminoesters promoted by Silver(I) complexes of chiral imines

F. Colombo
Primo
;
R. Annunziata
Secondo
;
M. Benaglia
Ultimo
2007

Abstract

The catalytic enantioselective addition of allyltributylstannane to N-protected greek small letter alpha-iminoesters promoted by silver(I) trifluoromethanesulfonate in the presence of chiral imine ligands was studied. After testing several chiral imines derived from 1,2-diaminocyclohexane and binaphthyl diamine a very simple experimental procedure was developed that allowed us to obtain optically active homoallylic amines in very high yields and enantioselectivities up to 71%.
Chiral catalysts; Chiral imines; Enantioselective catalysis; Homoallylic amines; Silver complex
Settore CHIM/06 - Chimica Organica
2007
http://hdl.handle.net/2434/36205
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/36205
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