The catalytic enantioselective addition of allyltributylstannane to N-protected greek small letter alpha-iminoesters promoted by silver(I) trifluoromethanesulfonate in the presence of chiral imine ligands was studied. After testing several chiral imines derived from 1,2-diaminocyclohexane and binaphthyl diamine a very simple experimental procedure was developed that allowed us to obtain optically active homoallylic amines in very high yields and enantioselectivities up to 71%.
Catalytic, enantioselective allylation of alfa-iminoesters promoted by Silver(I) complexes of chiral imines / F. Colombo, R. Annunziata, M. Benaglia. - In: TETRAHEDRON LETTERS. - ISSN 0040-4039. - 48:15(2007), pp. 2687-2690.
|Titolo:||Catalytic, enantioselective allylation of alfa-iminoesters promoted by Silver(I) complexes of chiral imines|
COLOMBO, FEDERICA (Primo)
ANNUNZIATA, RITA MARIA (Secondo)
BENAGLIA, MAURIZIO (Ultimo)
|Parole Chiave:||Chiral catalysts; Chiral imines; Enantioselective catalysis; Homoallylic amines; Silver complex|
|Settore Scientifico Disciplinare:||Settore CHIM/06 - Chimica Organica|
|Data di pubblicazione:||2007|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1016/j.tetlet.2007.02.071|
|Appare nelle tipologie:||01 - Articolo su periodico|