In this work, we provide a computational study of the effects of carotid endarterectomy (CEA) on the fluid-dynamics at internal carotid bifurcations. We perform numerical simulations in real geometries of the same patients before and after CEA, using patient-specific boundary data obtained by Echo-Color Doppler measurements. We analyze four patients with a primary closure and other four where a patch was used to close arteriotomies. The results show that (i) CEA is able to restore physiological fluid-dynamic conditions; (ii) among the post-operative cases, the presence of patch leads to local hemodynamic conditions which might imply a higher risk of restenosis in comparison with the cases without patch.

Computational study of the fluid-dynamics in carotids before and after endarterectomy / B. Guerciotti, C. Vergara, L. Azzimonti, L. Forzenigo, A. Buora, P. Biondetti, M. Domanin. - In: JOURNAL OF BIOMECHANICS. - ISSN 0021-9290. - 49:1(2016 Jan 04), pp. 26-38.

Computational study of the fluid-dynamics in carotids before and after endarterectomy

A. Buora;M. Domanin
Ultimo
2016

Abstract

In this work, we provide a computational study of the effects of carotid endarterectomy (CEA) on the fluid-dynamics at internal carotid bifurcations. We perform numerical simulations in real geometries of the same patients before and after CEA, using patient-specific boundary data obtained by Echo-Color Doppler measurements. We analyze four patients with a primary closure and other four where a patch was used to close arteriotomies. The results show that (i) CEA is able to restore physiological fluid-dynamic conditions; (ii) among the post-operative cases, the presence of patch leads to local hemodynamic conditions which might imply a higher risk of restenosis in comparison with the cases without patch.
carotids; CFD; endarterectomy; restenosis
Settore MED/22 - Chirurgia Vascolare
Settore MAT/08 - Analisi Numerica
4-gen-2016
18-nov-2015
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/361104
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