Background : patent ductus arteriosus (PDA) is one of the most common congenital heart defects in the dog and percutaneous closure is effective in achieving ductal closure.PDA closure is associated with abrupt hemodynamic changes. Hypothesis: A marked reduction in standard parameters of systolic function as assessed by M/B mode after PDA closure was identified in previous studies. Speckle-tracking echocardiography(STE) can provide further insight into the effect of PDA closure on cardiac mechanics in dogs affected by PDA. Animals: 25 client owned dogs affected by PDA Methods: Prospective study. Complete echocardiographic evaluation was performed before and 24 hours after PDA closure, including standard (EDVIB/M, ESVIB/M, AlloD/S, Qp/Qs, SI, EF and FS) and STE (global longitudinal, radial, transversal and circumferential strain and strain rate). Results: PDA closure was associated with a statistically significant decrease in conventional echocardiographic parameters and a derease in the absolute values of radial, transversal and circumferential S and SR, while longitudinal S and SR did not change significantly. Conclusion and clinical importance: PDA closure by percutaneous approach is associated with a marked decrease of conventional echocardiographic parameters due to the changes in loading conditions, but no evidence of systolic dysfunction was identified by means of STE, as none of the S and SR values were below normal ranges. In the short term, contractility is enhanced in the long axis (as Long S/SR values were not statistically different before and after closure) and normalizes in the short axis (circumferential, radial and transversal S/SR decreased to normal reference range).
Speckle tracking echocardiography in dogs with patent ductus arteriosus : effect of percutaneous closure on cardiac mechanics / I. Spalla, C. Locatelli, A. Zanaboni, P. Brambilla, C. Bussadori. - In: JOURNAL OF VETERINARY INTERNAL MEDICINE. - ISSN 1939-1676. - 30:3(2016 Jun), pp. 714-721.
|Titolo:||Speckle tracking echocardiography in dogs with patent ductus arteriosus : effect of percutaneous closure on cardiac mechanics|
|Parole Chiave:||congenital heart disease; dogs; strain; strain rate|
|Settore Scientifico Disciplinare:||Settore VET/08 - Clinica Medica Veterinaria|
Settore INF/01 - Informatica
|Data di pubblicazione:||giu-2016|
|Data ahead of print / Data di stampa:||2016|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1111/jvim.13919|
|Appare nelle tipologie:||01 - Articolo su periodico|