A 43-year-old male with a history of congenital hepatic fibrosis associated with large liver cell dysplasia developed a sizable lesion in the right lobe of the liver, which was, after a follow-up of 4 years, surgically removed on account of a suspected malignant transformation. Pathological examination showed an unencapsulated nodule with both architectural and cytological dysplastic changes, arising in a background of congenital hepatic fibrosis harbouring extranodularfoci of large liver cell dysplasia. This report concerns the development of a high grade dysplastic nodule, a sizable hepatocellular lesion with suspected preneoplastic significance, in a patient with congenital hepatic fibrosis associated with large liver cell dysplasia. Key words: congenital hepatic fibrosis; dysplastic nodule; liver cell: dysplasia.

DEVELOPMENT OF A HIGH GRADE DYSPLASTIC NODULE IN A CASE OF CONGENITAL HEPATIC FIBROSIS / M. RONCALLI, M. MAGGIONI, E. OPOCHER, G. COGGI. - In: ITALIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. - ISSN 1125-8055. - 31:4(1999), pp. 301-304.

DEVELOPMENT OF A HIGH GRADE DYSPLASTIC NODULE IN A CASE OF CONGENITAL HEPATIC FIBROSIS

M. RONCALLI
Primo
;
E. OPOCHER
Penultimo
;
G. COGGI
Ultimo
1999

Abstract

A 43-year-old male with a history of congenital hepatic fibrosis associated with large liver cell dysplasia developed a sizable lesion in the right lobe of the liver, which was, after a follow-up of 4 years, surgically removed on account of a suspected malignant transformation. Pathological examination showed an unencapsulated nodule with both architectural and cytological dysplastic changes, arising in a background of congenital hepatic fibrosis harbouring extranodularfoci of large liver cell dysplasia. This report concerns the development of a high grade dysplastic nodule, a sizable hepatocellular lesion with suspected preneoplastic significance, in a patient with congenital hepatic fibrosis associated with large liver cell dysplasia. Key words: congenital hepatic fibrosis; dysplastic nodule; liver cell: dysplasia.
Settore MED/18 - Chirurgia Generale
Settore MED/08 - Anatomia Patologica
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/35982
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