Mobile medical ignorance APP (MOMIA) : a new tool for promoting questions, questioning and questioners (Q3)- anytime, anywhere, anyone

OBJECTIVES/SPECIFIC AIMS: Develop a mobile app for our interactive Virtual Clinical Research Center/Questionarium (VCRC/Q) to elicit, collect and analyze the expanding Unknowns/Questions (“ignoramics”) accompanying the exploding Knowns/Answers (informatics) in translational science to investigate, showcase and enhance research advances and inquiry-based training, conferencing, networking and community outreach. METHODS/STUDY POPULATION: Progressive iterations of MoMIA were designed/tested for user friendliness, functionality and efficacy to reprogram our VCRC/Q Web-based platform “grid” for universal/ubiquitous access to Questions, Questioning and Questioners. Since the mid-1980s, our NIH-funded Curriculum and Summer Institute on Medical Ignorance has involved thousands of diverse questioning medical, undergraduate, high school student and other research trainees as well as professional scientists (including Nobel Laureates) and the general public. RESULTS/ANTICIPATED RESULTS: MoMIA is a Web-based tool (curiosityforall.org) adapted for mobile phones to rapidly and conveniently collect questions from multiple simultaneous users for sorting and future analysis. The VCRC/Q's full menu of resources can be combined with MoMIA to create a customized versions of our Curriculum on Translating Translation and Scientific Questioning in the “Explorarium” site. MoMIA can be demonstrated on your phone at ACTS 2015. DISCUSSION/SIGNIFICANCE OF IMPACT: MoMIA promises to enhance linkage to VCRC/Q resources thereby transforming the grid to promote questions, questioning, and questioners—the engine of translational and all science. Semantics and algorithms are being developed to study the questioning process (“curiosity”), gather key unanswered questions related to biomedical topics for research/action agendas, and encourage new ways of training, conferencing and networking around the expanding ignorance, thereby counterbalancing the megadata explosion in information.