Sub-threshold psychotic symptoms are quite commonly present in general population. Among these, Magical Ideation (MI) has been proved to be a valid predictor of psychosis. However, the genetic and environmental influences on the interplay between MI and personality have not fully been explored. A total of 534 adult twins from the population-based Italian Twin Register were assessed for MI using the MI Scale (MIS) and for personality with the temperament and character inventory (TCI). A Multivariate Cholesky model was applied with Mx statistical program. The best-fitting model showed that additive genetic and unshared environmental factors explain approximately the same proportion of variance in MI, whereas a less strong genetic influence on personality traits emerged. Relevant correlations between MI and specific personality traits (novelty seeking, cooperativeness, self-directedness, self-transcendence) were found, suggesting shared influences for MI and these traits. Both genetic and environmental factors explained these correlations, with genetic factors playing a predominant role. Moderate-to-substantial genetic effects on MI and personality were found. Shared genetic and environmental effects underlie the phenotypic correlation between MI (psychosis-proneness) and personality traits, i.e. self-directedness (negative association) and self-transcendence (positive association), potentially representing predictive markers of psychosis liability related to schizotypy and personality.
|Titolo:||Genetic and environmental bases of the interplay between magical ideation and personality|
|Parole Chiave:||Magical ideation; Psychosis; Schizotypy; Self-directedness; Self-transcendence; Temperament and character inventory; Twins; Adolescent; Adult; Aged; Character; Diseases in Twins; Female; Gene-Environment Interaction; Health Surveys; Humans; Male; Middle Aged; Personality Inventory; Phenotype; Psychotic Disorders; Registries; Temperament; Young Adult; Personality; Social Environment; Twins; Psychiatry and Mental Health; Biological Psychiatry; Medicine (all)|
|Settore Scientifico Disciplinare:||Settore MED/25 - Psichiatria|
|Data di pubblicazione:||2014|
|Digital Object Identifier (DOI):||10.1016/j.psychres.2013.11.021|
|Appare nelle tipologie:||01 - Articolo su periodico|