Natural network-structured hydrogels (e.g. bacterial cellulose (BC)) can be synthesised with specific artificial hydrogels (e.g. poly(2-hydroxyethyl methacrylate) (PHEMA)) to form a tougher and stronger nanofibre-reinforced composite hydrogel, which possesses micro-and nano-porous structure. These synthetic hydrogels exhibit a number of advantages for biomedical applications, such as good biocompatibility and better permeability for molecules to pass through. In this paper, the mechanical properties of this nanofibre-reinforced hydrogel containing BC and PHEMA have been characterised in terms of their tangent modulus and fracture stress/strain by uniaxial compressive testing. Numerical simulations based on Mooney-Rivlin hyperelastic theory are also conducted to understand the internal stress distribution and possible failure of the nanofibre-reinforced hydrogel under compression. By comparing the mechanical characteristics of BC, PHEMA, and PHEMA-based nanofibre reinforced hydrogel (BC-PHEMA) under the compression, it is possible to develop a suitable scaffold for tissue engineering on the basis of fundamental understanding of mechanical and fracture behaviours of nanofibre-reinforced hydrogels.
|Titolo:||Microstructural and mechanical characteristics of PHEMA-based nanofibre-reinforced hydrogel under compression|
LENARDI, CRISTINA (Penultimo)
|Parole Chiave:||A. 3-Dimensional reinforcement; B. Fracture; B. Mechanical properties; C. Computational modelling; C. Finite element analysis (FEA); Ceramics and Composites; Mechanics of Materials; Industrial and Manufacturing Engineering; Mechanical Engineering|
|Settore Scientifico Disciplinare:||Settore FIS/01 - Fisica Sperimentale|
|Data di pubblicazione:||2015|
|Digital Object Identifier (DOI):||10.1016/j.compositesb.2015.02.033|
|Appare nelle tipologie:||01 - Articolo su periodico|