Mixed epithelial and stromal tumor of the kidney is a recently recognized category of lesions occurring mostly in adult, middle-age women with a history of hormonal treatment. We present a rare case of a 58-year-old asymptomatic man without a history of hormonal treatment with a tumor characterized by proliferation of multiple cysts lined by single layers of epithelial cells and hypercellular stroma of spindle "ovarian-like" cells. Immunohistochemically, the stromal cells reacted against estrogen and progesterone receptors, vimentin, desmin, and CD34. A follow-up computed tomography scan performed 8 months after surgical enucleation of the lesion showed no signs of recurrence.
Non-hormone-induced mixed epithelial and stromal tumor of kidney in a man : description of a rare case / P. Colombo, R. Naspro, L. Vallieri, I. Vavassori, S. Valenti, C. Galli, M. Roncalli. - In: UROLOGY. - ISSN 0090-4295. - 2008:71(2008), pp. 178e7-178e9. [10.1016/j.urology.2007.09.057]
Non-hormone-induced mixed epithelial and stromal tumor of kidney in a man : description of a rare case
M. Roncalli
2008
Abstract
Mixed epithelial and stromal tumor of the kidney is a recently recognized category of lesions occurring mostly in adult, middle-age women with a history of hormonal treatment. We present a rare case of a 58-year-old asymptomatic man without a history of hormonal treatment with a tumor characterized by proliferation of multiple cysts lined by single layers of epithelial cells and hypercellular stroma of spindle "ovarian-like" cells. Immunohistochemically, the stromal cells reacted against estrogen and progesterone receptors, vimentin, desmin, and CD34. A follow-up computed tomography scan performed 8 months after surgical enucleation of the lesion showed no signs of recurrence.
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