The complete 1H and 13C NMR assignments are reported for the antithrombotic (21R)- and (21S)-argatroban by 1D and 2D NMR experiments (HSQC, HMBC, NOESY and 1H--1H COSY). Some well-resolved signals could be used for an accurate measurement of the diastereomeric composition of argatroban. Copyright (c) 2007 John Wiley & Sons, Ltd.
Complete 1H and 13C assignments of (21R) and (21S) diastereomers of argatroban / D.R. Colombo, P. Ferraboschi, P. Grisenti, L. Legnani. - In: MAGNETIC RESONANCE IN CHEMISTRY. - ISSN 0749-1581. - 46:1(2008), pp. 99-102.
Complete 1H and 13C assignments of (21R) and (21S) diastereomers of argatroban
D.R. ColomboPrimo
;P. FerraboschiSecondo
;
2008
Abstract
The complete 1H and 13C NMR assignments are reported for the antithrombotic (21R)- and (21S)-argatroban by 1D and 2D NMR experiments (HSQC, HMBC, NOESY and 1H--1H COSY). Some well-resolved signals could be used for an accurate measurement of the diastereomeric composition of argatroban. Copyright (c) 2007 John Wiley & Sons, Ltd.
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