Latex beads coated with secretory immunoglobulin (IgA) instilled into mouse intestinal loops are taken up by M cells present in Peyer's patch follicle-associated epithelial tissue. Bead adsorption and uptake is greater at the edge compared with the apex of follicle domes. Coating beads with bovine serum albumin (BSA) causes a fourfold reduction in adsorption and a twentyfold reduction in uptake. Results demonstrate selectivity between adsorption and uptake and between the ability of different proteins to facilitate uptake.
|Titolo:||Confocal analysis of fluorescent bead uptake by mouse Peyer's patch follicle-associated M cells|
|Autori interni:||PORTA, CRISTINA EUGENIA HILDE (Primo)|
CREMASCHI, DARIO (Ultimo)
|Data di pubblicazione:||1992|
|Digital Object Identifier (DOI):||10.1113/expphysiol.1992.sp003662|
|Appare nelle tipologie:||01 - Articolo su periodico|