The antibacterial activity of cyclohexane, dichlormethane, methanol and aqueous extracts of tinder fun-gus Fomes fomentarius (L.) Fr (Polyporaceae) was tested against 9 bacterial strains (Staphylococcus aureus,Staphylococcus epidermidis, Micrococcus luteus, Bacillus subtilis, Enterococcus feacalis, Escherichia coli, Kleb-siella pneumoniae, Pseudomonas aeruginosa, Salmonella abony), as well as against 10 different clinicalisolates and one reference strain of Helicobacter pylori. Minimal inhibitory concentrations (MICs) of allextracts against 9 bacterial strains were in the range of 125–250 g/ml. Methanol and aqueous extractsshowed significant activity against H. pylori with MIC values between 4–32 g/ml. Also, cytotoxicity oftested extracts was significant. Aqueous extract was the most active one against HeLa cells with an IC508.31 ± 1.18 g/ml and N87 cells with IC5064.46 ± 3.13 g/ml without any activity against normal MRC5cell line (> 200 g/ml).
Antibacterial and cytotoxic activities of wild mushroom Fomesfomentarius (L.) Fr., polyporaceae / M. Kolundzic, N.Ð. Grozdanici, M. Dodevska, M. Milenkovic, F. Sisto, A. Miani, G. Farronato, T. Kundakovic. - In: INDUSTRIAL CROPS AND PRODUCTS. - ISSN 0926-6690. - 79(2016), pp. 110-115. [10.1016/j.indcrop.2015.10.030]
Antibacterial and cytotoxic activities of wild mushroom Fomesfomentarius (L.) Fr., polyporaceae
F. Sisto;A. Miani;G. FarronatoPenultimo
;
2016
Abstract
The antibacterial activity of cyclohexane, dichlormethane, methanol and aqueous extracts of tinder fun-gus Fomes fomentarius (L.) Fr (Polyporaceae) was tested against 9 bacterial strains (Staphylococcus aureus,Staphylococcus epidermidis, Micrococcus luteus, Bacillus subtilis, Enterococcus feacalis, Escherichia coli, Kleb-siella pneumoniae, Pseudomonas aeruginosa, Salmonella abony), as well as against 10 different clinicalisolates and one reference strain of Helicobacter pylori. Minimal inhibitory concentrations (MICs) of allextracts against 9 bacterial strains were in the range of 125–250 g/ml. Methanol and aqueous extractsshowed significant activity against H. pylori with MIC values between 4–32 g/ml. Also, cytotoxicity oftested extracts was significant. Aqueous extract was the most active one against HeLa cells with an IC508.31 ± 1.18 g/ml and N87 cells with IC5064.46 ± 3.13 g/ml without any activity against normal MRC5cell line (> 200 g/ml).File | Dimensione | Formato | |
---|---|---|---|
Sisto Francesca.pdf
accesso riservato
Tipologia:
Publisher's version/PDF
Dimensione
280.46 kB
Formato
Adobe PDF
|
280.46 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.