The antibacterial activity of cyclohexane, dichlormethane, methanol and aqueous extracts of tinder fun-gus Fomes fomentarius (L.) Fr (Polyporaceae) was tested against 9 bacterial strains (Staphylococcus aureus,Staphylococcus epidermidis, Micrococcus luteus, Bacillus subtilis, Enterococcus feacalis, Escherichia coli, Kleb-siella pneumoniae, Pseudomonas aeruginosa, Salmonella abony), as well as against 10 different clinicalisolates and one reference strain of Helicobacter pylori. Minimal inhibitory concentrations (MICs) of allextracts against 9 bacterial strains were in the range of 125–250 g/ml. Methanol and aqueous extractsshowed significant activity against H. pylori with MIC values between 4–32 g/ml. Also, cytotoxicity oftested extracts was significant. Aqueous extract was the most active one against HeLa cells with an IC508.31 ± 1.18 g/ml and N87 cells with IC5064.46 ± 3.13 g/ml without any activity against normal MRC5cell line (> 200 g/ml).
Antibacterial and cytotoxic activities of wild mushroom Fomesfomentarius (L.) Fr., polyporaceae / M. Kolundzic, N.Ð. Grozdanici, M. Dodevska, M. Milenkovic ,F. Sisto, A. Miani, G. Farronato, T. Kundakovic. - In: INDUSTRIAL CROPS AND PRODUCTS. - ISSN 0926-6690. - 79(2016), pp. 110-115.
Titolo: | Antibacterial and cytotoxic activities of wild mushroom Fomesfomentarius (L.) Fr., polyporaceae |
Autori: | FARRONATO, GIAMPIETRO (Penultimo) |
Parole Chiave: | Antibacterial activity; Cytotoxicity |
Settore Scientifico Disciplinare: | Settore MED/07 - Microbiologia e Microbiologia Clinica Settore MED/28 - Malattie Odontostomatologiche Settore MED/50 - Scienze Tecniche Mediche Applicate |
Data di pubblicazione: | 2016 |
Rivista: | |
Tipologia: | Article (author) |
Data ahead of print / Data di stampa: | 12-ott-2015 |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1016/j.indcrop.2015.10.030 |
Appare nelle tipologie: | 01 - Articolo su periodico |
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