Second-generation antihistamines are unquestionably the first-line treatment for chronic urticaria and can be used at higher than licensed doses if normal doses fail to control the disease. A short course of oral corticosteroids should be considered for patients not responding to antihistamines before trying other immunosuppressive drugs. Ciclosporin is effective in most antihistamine-resistant patients who require long-term corticosteroid treatments to control their disease. Omalizumab is effective in most subsets of chronic urticaria sufferers who do not respond to other treatments but its high cost represents a limitation to its widespread use. © 2014 Elsevier Inc.
Treatment of Chronic Urticaria / R. Asero, A. Tedeschi, M. Cugno. - In: IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA. - ISSN 0889-8561. - 34:1(2014 Feb), pp. 105-116. [10.1016/j.iac.2013.09.013]
Treatment of Chronic Urticaria
M. CugnoUltimo
2014
Abstract
Second-generation antihistamines are unquestionably the first-line treatment for chronic urticaria and can be used at higher than licensed doses if normal doses fail to control the disease. A short course of oral corticosteroids should be considered for patients not responding to antihistamines before trying other immunosuppressive drugs. Ciclosporin is effective in most antihistamine-resistant patients who require long-term corticosteroid treatments to control their disease. Omalizumab is effective in most subsets of chronic urticaria sufferers who do not respond to other treatments but its high cost represents a limitation to its widespread use. © 2014 Elsevier Inc.Pubblicazioni consigliate
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