In the rapidly evolving field of tissue engineering, continuous advances are required to improve scaffold design and fabrication to obtain biomimetic supports for cell adhesion, proliferation, penetration and differentiation. Both electrospun fibrous scaffolds and hydrogels are widely used in this field since they well reproduce the structure of the extracellular matrix (ECM) of many biological tissues. Limitations of these two types of materials can be overcome through their combination, by developing composite structures 1, combining enhanced mechanical properties (provided by the fibrous components) and improved cell penetration (provided by the gel phase) into a superior ability to mimic natural ECM, which is constituted by both a fibrous protein network and a hydrogel matrix.
Atmospheric pressure non-thermal plasma for the production of composite materials / N. Bloise, M. Sampaolesi, L. Visai, V. Colombo, M. Gherardi, M.L. Focarete, C. Gualandi, R. Laurita, A. Liguori, N. Mauro, A. Manfredi, P. Ferruti, E. Ranucci - In: Plasma Sciences (ICOPS), 2015 IEEE International Conference on[s.l] : IEEE, 2015. - pp. 1-1 (( Intervento presentato al 42. convegno IEEE International Conference on Plasma Science tenutosi a Antalya nel 2015 [10.1109/PLASMA.2015.7179970].
Atmospheric pressure non-thermal plasma for the production of composite materials
A. Manfredi;E. RanucciUltimo
2015
Abstract
In the rapidly evolving field of tissue engineering, continuous advances are required to improve scaffold design and fabrication to obtain biomimetic supports for cell adhesion, proliferation, penetration and differentiation. Both electrospun fibrous scaffolds and hydrogels are widely used in this field since they well reproduce the structure of the extracellular matrix (ECM) of many biological tissues. Limitations of these two types of materials can be overcome through their combination, by developing composite structures 1, combining enhanced mechanical properties (provided by the fibrous components) and improved cell penetration (provided by the gel phase) into a superior ability to mimic natural ECM, which is constituted by both a fibrous protein network and a hydrogel matrix.File | Dimensione | Formato | |
---|---|---|---|
07179970.pdf
accesso riservato
Tipologia:
Publisher's version/PDF
Dimensione
69.38 kB
Formato
Adobe PDF
|
69.38 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.