The present invention relates to the use of amphoteric polyamidoamines with MW of 10-100 kDa as carriers of antimalarial drugs and to formulations thereof. Formulation of a pharmaceutical compn. contg. ISA23 and chloroquine was disclosed and its antimalarial activity was shown in vitro.
Amphoteric polyamidoamines in the treatment of malaria / E. Ranucci, P. Ferruti, F. Fenili, A. Manfredi, N. Mauro, B. Fernandez, U. Xavier, Patricia.
Amphoteric polyamidoamines in the treatment of malaria
E. Ranucci;
2014
Abstract
The present invention relates to the use of amphoteric polyamidoamines with MW of 10-100 kDa as carriers of antimalarial drugs and to formulations thereof. Formulation of a pharmaceutical compn. contg. ISA23 and chloroquine was disclosed and its antimalarial activity was shown in vitro.
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