We evaluated the association between MCP-1, CCR2, RANTES, and CCR5 gene polymorphisms and upper urinary tract infection in 273 children recruited in Northeast Italy. Statistical analysis of RANTES-403 G>A genotype frequencies showed that children carrying the RANTES-403 G allele are at higher risk for urinary tract infection, irrespective of vesicoureteral reflux.
Upper urinary tract infections are associated with RANTES promoter polymorphism / S. Centi, S. Negrisolo, A. Stefanic, E. Benetti, W. Cassar, L. Da Dalt, W. Rigamonti, P. Zucchetta, G. Montini, L. Murer, L. Artifoni. - In: THE JOURNAL OF PEDIATRICS. - ISSN 0022-3476. - 157:6(2010 Dec), pp. 1038-1040.
Upper urinary tract infections are associated with RANTES promoter polymorphism
G. Montini;
2010
Abstract
We evaluated the association between MCP-1, CCR2, RANTES, and CCR5 gene polymorphisms and upper urinary tract infection in 273 children recruited in Northeast Italy. Statistical analysis of RANTES-403 G>A genotype frequencies showed that children carrying the RANTES-403 G allele are at higher risk for urinary tract infection, irrespective of vesicoureteral reflux.
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