A novel concept of saccharide vaccines is described. These are formed by multivalent and multi-functional systems in which synthetic antigens and adjuvants of the immune system are linked to a central core of Au nanoparticles, dendrimers, or magnetic Fe oxides nanoparticles. A family of synthetic antigens formed by analogs of the repeating unit of the bacterium Neisseria meningitidis type A is described.
Saccharide vaccines of new type. Contribution from organic chemistry / G. Russo. - In: LA CHIMICA E L'INDUSTRIA. - ISSN 0009-4315. - 88:6(2006), pp. 88-92.
Saccharide vaccines of new type. Contribution from organic chemistry
G. Russo
2006
Abstract
A novel concept of saccharide vaccines is described. These are formed by multivalent and multi-functional systems in which synthetic antigens and adjuvants of the immune system are linked to a central core of Au nanoparticles, dendrimers, or magnetic Fe oxides nanoparticles. A family of synthetic antigens formed by analogs of the repeating unit of the bacterium Neisseria meningitidis type A is described.
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