This paper deals with some basic statistical issues arising from biological monitoring. Data description, Gaussianity tests, outlier identification, parametric and non-parametric estimates of fractiles and their standard errors, and parametric estimate of the one tail upper side tolerance interval are treated and exemplified using two data sets. Sample size and power determination are considered in terms of the cut-off point of the diagnostic quantitative test.
Statistical aspects of the estimation of reference limits / P. Duca. - In: SCIENCE OF THE TOTAL ENVIRONMENT. - ISSN 0048-9697. - 120:1-2(1992 Jun 09), pp. 155-171. ((Intervento presentato al convegno Workshop on from Macro to Microdoses : reference values for toxic metals tenutosi a Monticelli Brusati nel 1990.
Statistical aspects of the estimation of reference limits
P. DucaPrimo
1992
Abstract
This paper deals with some basic statistical issues arising from biological monitoring. Data description, Gaussianity tests, outlier identification, parametric and non-parametric estimates of fractiles and their standard errors, and parametric estimate of the one tail upper side tolerance interval are treated and exemplified using two data sets. Sample size and power determination are considered in terms of the cut-off point of the diagnostic quantitative test.
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