We report a noteworthy case of a 7-month-old infant who suddenly and unexpectedly died during her sleep. After a complete postmortem examination, review of the clinical history, and detailed death scene investigation, the death remained unexplained, leading to a diagnosis of sudden infant death syndrome. However, an extensive review of the brainstem neuropathology revealed a severe alteration in the area postrema (a highly vascular structure lying at the base of the fourth ventricle outside of the blood-brain barrier). The alteration was likely due to massive and repeated to a common household insecticide in the last few weeks of life. These results provide an explanation for this sudden infant death, allowing a differential diagnosis from sudden infant death syndrome.
Sudden infant death with area postrema lesion likely due to wrong use of insecticide / A.M. Lavezzi, A. Cappiello, V. Termopoli, E. Bonoldi, L. Matturri. - In: PEDIATRICS. - ISSN 0031-4005. - 136:4(2015 Oct), pp. e1039-e1042.
|Titolo:||Sudden infant death with area postrema lesion likely due to wrong use of insecticide|
LAVEZZI, ANNA MARIA (Primo)
MATTURRI, LUIGI (Ultimo)
|Parole Chiave:||area postrema; SIDS; insecticides|
|Settore Scientifico Disciplinare:||Settore MED/08 - Anatomia Patologica|
|Data di pubblicazione:||ott-2015|
|Data ahead of print / Data di stampa:||14-set-2015|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1542/peds.2015-0425|
|Appare nelle tipologie:||01 - Articolo su periodico|