: N-Alkyl and N-aryl 5-substituted oxazolidinones 12-19 were prepared in good to excellent yields by reaction of N-alkyl and N-aryl 1,2-amino alcohols 3-10 with S,S-dimethyldithiocarbonate (11) in the presence of solid NaOH under SL-PTC conditions. The procedure is particularly suitable for scale-up the process involving the use of cheap and ecosafe reagents under mild reaction conditions.
|Titolo:||S,S-Dimethyl Dithiocarbonate as a Valuable Starting Material for the Synthesis of 5-Substituted Oxazolidinones under Solid-Liquid Phase Transfer Catalysis (SL-PTC) Conditions|
|Autori interni:||LANDINI, DARIO|
|Parole Chiave:||1,2-amino alcohols; 5-substituted oxazolidinones; Carbonylation reaction; Phase-transfer catalysis; S,S-dimethyldithiocarbonate|
|Settore Scientifico Disciplinare:||Settore CHIM/04 - Chimica Industriale|
|Data di pubblicazione:||nov-2006|
|Appare nelle tipologie:||01 - Articolo su periodico|