A review on 1,3-dipolar cycloaddns. in aq. media represents a useful, non conventional protocol in the synthesis of a variety of five-membered heterocycles. In addn., water as the solvent may significantly enhance cycloaddn. rates and/or stereoslectivities. Further, the literature data on this subject are reviewed in a systematic way, with an emphasis to improvements with respect to cycloaddns. performed in the usual, non-aq. conditions.
1,3-Dipolar cycloadditions in aqueous media / G. Molteni. - In: HETEROCYCLES. - ISSN 0385-5414. - 68:10(2006), pp. 2177-2203.
1,3-Dipolar cycloadditions in aqueous media
G. Molteni
2006
Abstract
A review on 1,3-dipolar cycloaddns. in aq. media represents a useful, non conventional protocol in the synthesis of a variety of five-membered heterocycles. In addn., water as the solvent may significantly enhance cycloaddn. rates and/or stereoslectivities. Further, the literature data on this subject are reviewed in a systematic way, with an emphasis to improvements with respect to cycloaddns. performed in the usual, non-aq. conditions.
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