The application of reductive carbonylation of nitroarenes to the synthesis of fine chemicals is described. The review focuses on the results reported from 1996 onwards and is mainly divided in two parts, respectively describing the intra-molecular cyclization reactions of nitroarenes bearing in the ortho position a suitable functional group and the intermolecular reactions of nitroarenes with external olefins and alkynes. Benzo-fused heterocycles such as indoles and quinolinones are obtained by the first group of reactions, whereas allylic amines, oxazines, pyrroles and indoles are the products of inter-molecular reactions. Mechanistic studies are also discussed in a separate section.

Fine chemicals by reductive carbonyllation of nitroarenes, catalyzed by transition metal complexes / F. Ragaini, S. Cenini, E. Gallo, A. Caselli, S. Fantauzzi. - In: CURRENT ORGANIC CHEMISTRY. - ISSN 1385-2728. - 10:12(2006), pp. 1479-1510.

Fine chemicals by reductive carbonyllation of nitroarenes, catalyzed by transition metal complexes

F. Ragaini;S. Cenini;E. Gallo;A. Caselli;S. Fantauzzi
2006

Abstract

The application of reductive carbonylation of nitroarenes to the synthesis of fine chemicals is described. The review focuses on the results reported from 1996 onwards and is mainly divided in two parts, respectively describing the intra-molecular cyclization reactions of nitroarenes bearing in the ortho position a suitable functional group and the intermolecular reactions of nitroarenes with external olefins and alkynes. Benzo-fused heterocycles such as indoles and quinolinones are obtained by the first group of reactions, whereas allylic amines, oxazines, pyrroles and indoles are the products of inter-molecular reactions. Mechanistic studies are also discussed in a separate section.
C-H functionalization; palladium-phenanthroline complexes; highly efficient promoters; carbon-monoxide; N-heterocyclization; allylic amination; carbonylation reactions; methyl phenycarbamate; phosphorus-acids; nitro-compounds
Settore CHIM/03 - Chimica Generale e Inorganica
CURRENT ORGANIC CHEMISTRY
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/30085
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