The diagnosis of Cushing’s syndrome requires a high degree of suspicion and this may lead to testing of patients with some, but not all, features of hypercortisolism due to causes other than adrenal/pituitary dysfunction. Indeed, conditions such as depression, alcoholism, obesity and polycystic ovary syndrome may be accompanied by Cushing’s-like physical and biochemical changes and are therefore grouped under the heading of “pseudoCushing”. This review will summarize clinical and biochemical findings in pseudoCushing’s states and describe the differential diagnosis with Cushing’s syndrome.

Laboratorial diagnosis of Cushing’s Syndrome: differential diagnosis with pseudo Cushing’s conditions as obesity, alcoholism and depression / M. De Martin, F. Pecori Giraldi, F. Cavagnini - In: Cushing's syndrome / [a cura di] M.D. Bronstein. - New York : Springer, 2011. - ISBN 9781603274487. - pp. 65-78

Laboratorial diagnosis of Cushing’s Syndrome: differential diagnosis with pseudo Cushing’s conditions as obesity, alcoholism and depression

F. Pecori Giraldi
Secondo
;
2011

Abstract

The diagnosis of Cushing’s syndrome requires a high degree of suspicion and this may lead to testing of patients with some, but not all, features of hypercortisolism due to causes other than adrenal/pituitary dysfunction. Indeed, conditions such as depression, alcoholism, obesity and polycystic ovary syndrome may be accompanied by Cushing’s-like physical and biochemical changes and are therefore grouped under the heading of “pseudoCushing”. This review will summarize clinical and biochemical findings in pseudoCushing’s states and describe the differential diagnosis with Cushing’s syndrome.
Cushing’s syndrome; pseudoCushing; alcoholism; obesity; depression; polycystic ovary syndrome; diagnosis urinary; free cortisol; dexamethasone suppression; test cortisol circadian; rhythm
Settore MED/13 - Endocrinologia
2011
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/300470
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