The purpose of this project is monitoring different parameters in a T1DM patient using an insulin pump with a Continuous Glucose Monitoring System (CGMS) performing a 3 weeks walking exercise (700 km). In a 40 years old T1DM patient we evaluated body composition by bioelectrical impedance analysis, continuously monitored the glycemic profile for 3 weeks via CGMS, and evaluated the energy expenditure 3 days each week during the walking. We registered a decrease in total body weight (PRE=83.5 to POST=81.1 kg) and fat mass (PRE=12.2 to POST=8.9 kg), and an increase in fat free mass plus water (PRE=71.3 to POST=72.9 kg). The CGMS data showed a 9 % decrease in the average glucose concentration comparing the first week (W1=133 mg/dl) to the third week (W3=121 mg/dl). The average daily insulin decrease by 12 % was (W1=38, to W3=33.5 IU), resulted from the sum of average daily basal insulin (W1=16.2 to W3=12.6 IU) and average daily insulin bolus (W1=21.8 to W3=20.9 IU). The % in which glucose level stayed on target [between 80 - 160 mg/dl] increase by 7% (W1 = 57 to W3= 64 %) and decrease by 8 % during hyperglycemia (W1=26 to W3 18%). Data showed that an aerobic exercise performed for 3 weeks can improve the glucose profile and the other metabolic parameters in a T1DM patient. A simple walking exercise without engaging in any risky high intensity -physical activity can have overall beneficial effects on health in a T1DM patients.

MONITORING DIFFERENT PARAMETERS DURING 3 WEEKS WALKING IN A TYPE 1 DIABETIC PATIENT WITH INSULIN PUMP AND CMGS / F. Casiraghi, S. Benedini, A. Ciucci, L. Luzi. - In: DIABETES TECHNOLOGY & THERAPEUTICS. - ISSN 1520-9156. - 16:suppl. 1(2014 Feb), pp. A51-A51. (Intervento presentato al 7. convegno International Conference on Advanced Technologies & Treatments for Diabetes (ATTD) tenutosi a Wien nel 2014) [10.1089/dia.2014.1515].

MONITORING DIFFERENT PARAMETERS DURING 3 WEEKS WALKING IN A TYPE 1 DIABETIC PATIENT WITH INSULIN PUMP AND CMGS

S. Benedini;L. Luzi
2014

Abstract

The purpose of this project is monitoring different parameters in a T1DM patient using an insulin pump with a Continuous Glucose Monitoring System (CGMS) performing a 3 weeks walking exercise (700 km). In a 40 years old T1DM patient we evaluated body composition by bioelectrical impedance analysis, continuously monitored the glycemic profile for 3 weeks via CGMS, and evaluated the energy expenditure 3 days each week during the walking. We registered a decrease in total body weight (PRE=83.5 to POST=81.1 kg) and fat mass (PRE=12.2 to POST=8.9 kg), and an increase in fat free mass plus water (PRE=71.3 to POST=72.9 kg). The CGMS data showed a 9 % decrease in the average glucose concentration comparing the first week (W1=133 mg/dl) to the third week (W3=121 mg/dl). The average daily insulin decrease by 12 % was (W1=38, to W3=33.5 IU), resulted from the sum of average daily basal insulin (W1=16.2 to W3=12.6 IU) and average daily insulin bolus (W1=21.8 to W3=20.9 IU). The % in which glucose level stayed on target [between 80 - 160 mg/dl] increase by 7% (W1 = 57 to W3= 64 %) and decrease by 8 % during hyperglycemia (W1=26 to W3 18%). Data showed that an aerobic exercise performed for 3 weeks can improve the glucose profile and the other metabolic parameters in a T1DM patient. A simple walking exercise without engaging in any risky high intensity -physical activity can have overall beneficial effects on health in a T1DM patients.
exercise; insulin pump; CMGS
Settore MED/13 - Endocrinologia
feb-2014
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/299798
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