DCs in the gut have specialized functions and are involved in maintaining intestinal homeostasis via tolerizing the microbiota and inducing immunity to pathogenic bacteria. Here, we summarize the characteristics of two major subtypes of phagocytes in the gut (CX3CR1(+) and CD103(+)) and pDCs and analyze their possible involvement in bacterial handling.
Dendritic cells in bacteria handling in the gut / M. Rescigno. - In: JOURNAL OF LEUKOCYTE BIOLOGY. - ISSN 0741-5400. - 90:4(2011 Oct), pp. 669-672.
Dendritic cells in bacteria handling in the gut
M. Rescigno
2011
Abstract
DCs in the gut have specialized functions and are involved in maintaining intestinal homeostasis via tolerizing the microbiota and inducing immunity to pathogenic bacteria. Here, we summarize the characteristics of two major subtypes of phagocytes in the gut (CX3CR1(+) and CD103(+)) and pDCs and analyze their possible involvement in bacterial handling.
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