The immune system, to protect the body, must discriminate between the pathogenic and non-pathogenic microbes and respond to them in different ways. How the mucosal immune system manages to make this distinction is poorly understood. We suggest here that the distinction between pathogenic and non-pathogenic microbes is made by an integrated system rather than by single types of cells or single types of receptors; a systems biology approach is needed to understand immune recognition.
|Titolo:||Systemic features of immune recognition in the gut|
RESCIGNO, MARIA (Secondo)
|Parole Chiave:||Immune recognition; Systems immunology; Pathogen; Pathogen-associated molecular pattern|
|Settore Scientifico Disciplinare:||Settore BIO/13 - Biologia Applicata|
|Data di pubblicazione:||nov-2011|
|Digital Object Identifier (DOI):||10.1016/j.micinf.2011.06.011|
|Appare nelle tipologie:||01 - Articolo su periodico|