The immune system, to protect the body, must discriminate between the pathogenic and non-pathogenic microbes and respond to them in different ways. How the mucosal immune system manages to make this distinction is poorly understood. We suggest here that the distinction between pathogenic and non-pathogenic microbes is made by an integrated system rather than by single types of cells or single types of receptors; a systems biology approach is needed to understand immune recognition.
Systemic features of immune recognition in the gut / B. Swiatczak, M. Rescigno, I. Cohen. - In: MICROBES AND INFECTION. - ISSN 1286-4579. - 13:12-13(2011 Nov), pp. 983-991.
Systemic features of immune recognition in the gut
M. RescignoSecondo
;
2011
Abstract
The immune system, to protect the body, must discriminate between the pathogenic and non-pathogenic microbes and respond to them in different ways. How the mucosal immune system manages to make this distinction is poorly understood. We suggest here that the distinction between pathogenic and non-pathogenic microbes is made by an integrated system rather than by single types of cells or single types of receptors; a systems biology approach is needed to understand immune recognition.
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