The coding sequences of five human enterovirus (HEV)-C genotype 105 strains recovered in Italy, Romania and Burundi from patients with upper and lower respiratory tract infections were analysed and phylogenetically compared with other circulating HEV-C strains. The EV-C105 was closely related to EV-C109 and EV-C118 strains. The European strains were similar to other circulating EV-C105 strains, while the two African EV-C105 clustered in separate bootstrapsupported (.0.90) branches of the P2 and P3 region trees. Minor inconsistencies in the clustering pattern of EV-C105 in the capsid region (P1) and non-capsid region (P3) suggest that recombination may have occurred in EV-C105 group B viruses. In conclusion, phylogenetic analysis revealed the circulation of two distinct EV-C105 lineages in Europe and Africa. A different pattern of evolution could be hypothesized for the two EV-C105 lineages.
|Titolo:||Circulation of two enterovirus C105 (EV-C105) lineages in Europe and Africa|
ESPOSITO, SUSANNA (Penultimo)
|Parole Chiave:||community-acquired pneumonia; respiratory-tract infection; maximum-likeihood; genomic analysis; recombination; children; phylogenies; rhinovirus; sequence; viruses|
|Settore Scientifico Disciplinare:||Settore MED/38 - Pediatria Generale e Specialistica|
|Data di pubblicazione:||giu-2015|
|Digital Object Identifier (DOI):||10.1099/vir.0.000088|
|Appare nelle tipologie:||01 - Articolo su periodico|