The chlorella virus PBCV-1 was the first virus found to encode a functional potassium channel protein (Kcv). Kcv is small (94 aa) and basically consists of the M1-P-M2 (membrane-pore-membrane) module typical of the pore regions of all known potassium channels. Kcv forms functional channels in three heterologous systems. This brief review discusses the gating, permeability and modulation properties of Kcv and compares them to the properties of bacterial and mammalian K+ channels.
The viral potassium channel Kcv: structural and functional features / S. Gazzarrini, M. Severino, M. Lombardi, M. Morandi, D. DiFrancesco, J.L. Van Etten, G. Thiel, A. Moroni. - In: FEBS LETTERS. - ISSN 0014-5793. - 552:1(2003), pp. 12-16.
The viral potassium channel Kcv: structural and functional features
S. Gazzarrini;D. DiFrancesco;A. Moroni
2003
Abstract
The chlorella virus PBCV-1 was the first virus found to encode a functional potassium channel protein (Kcv). Kcv is small (94 aa) and basically consists of the M1-P-M2 (membrane-pore-membrane) module typical of the pore regions of all known potassium channels. Kcv forms functional channels in three heterologous systems. This brief review discusses the gating, permeability and modulation properties of Kcv and compares them to the properties of bacterial and mammalian K+ channels.
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
