Hashimoto's encephalopathy (HE) is a rare neurological disorder with a heterogeneous group of neurological symptoms associated with high titres of anti-thyroid antibodies. Clinical manifestations may include encephalopathic features such as seizures, behavioural and psychiatric manifestations, movement disorders and coma. The objective of this presentation is to describe a patient with this rare and controversial clinical syndrome mimicking Creutzfeldt-Jakob disease, associated with a Hashimoto euthyroid thyroiditis and with a significant response to high dose intravenous prednisone. The responsiveness of this syndrome to steroids suggests that this disorder involves immune pathogenic mechanisms, as previous reviews reported.
Steroid-responsive Hashimoto encephalopathy mimicking Creutzfeldt-Jakob disease / D. Santoro, I. Colombo, I. Ghione, L. Peverelli, N. Bresolin, M. Sciacco, A. Prelle. - In: NEUROLOGICAL SCIENCES. - ISSN 1590-1874. - 32:4(2011 Aug 11), pp. 719-722.
Titolo: | Steroid-responsive Hashimoto encephalopathy mimicking Creutzfeldt-Jakob disease |
Autori: | |
Parole Chiave: | encephalopathy; Hashimoto; anti-thyroid antibodies; steroids |
Settore Scientifico Disciplinare: | Settore MED/26 - Neurologia |
Data di pubblicazione: | 11-ago-2011 |
Rivista: | |
Tipologia: | Article (author) |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1007/s10072-011-0610-8 |
Appare nelle tipologie: | 01 - Articolo su periodico |
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