Hashimoto's encephalopathy (HE) is a rare neurological disorder with a heterogeneous group of neurological symptoms associated with high titres of anti-thyroid antibodies. Clinical manifestations may include encephalopathic features such as seizures, behavioural and psychiatric manifestations, movement disorders and coma. The objective of this presentation is to describe a patient with this rare and controversial clinical syndrome mimicking Creutzfeldt-Jakob disease, associated with a Hashimoto euthyroid thyroiditis and with a significant response to high dose intravenous prednisone. The responsiveness of this syndrome to steroids suggests that this disorder involves immune pathogenic mechanisms, as previous reviews reported.
|Titolo:||Steroid-responsive Hashimoto encephalopathy mimicking Creutzfeldt-Jakob disease|
|Parole Chiave:||encephalopathy; Hashimoto; anti-thyroid antibodies; steroids|
|Settore Scientifico Disciplinare:||Settore MED/26 - Neurologia|
|Data di pubblicazione:||11-ago-2011|
|Digital Object Identifier (DOI):||10.1007/s10072-011-0610-8|
|Appare nelle tipologie:||01 - Articolo su periodico|