A range of high specific activity accelerator-produced radionuclides in no-carrier-added (NCA) form, for uses in metabolic radiotherapy and for PET, has been investigated. To this aim it was necessary optimizing the irradiation parameters by determining the excitation functions of the nuclear reactions involved, as needed for the following selective radiochemical separations of the radionuclides of interest. For the NCA radionuclides investigated, the spectrometry measurements, done at LASA-INFN on gamma, X and on a spectra are discussed together with the measurements of radionuclidic, radiochemical and chemical purities by analytical and radioanalytical techniques.
Result on accelerator production of innovative radionuclides for metabolic radiotherapy and PET and on relevant nuclear data / F. Groppi, M.L. Bonardi, E. Menapace, S. Morzenti, C. Zona, L. Canella, Z.B. Alfassi. - In: NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH. SECTION A, ACCELERATORS, SPECTROMETERS, DETECTORS AND ASSOCIATED EQUIPMENT. - ISSN 0168-9002. - 562:2(2006 Jun), pp. 1072-1075. [10.1016/j.nima.2006.02.098]
Result on accelerator production of innovative radionuclides for metabolic radiotherapy and PET and on relevant nuclear data
F. GroppiPrimo
;M.L. BonardiSecondo
;S. Morzenti;
2006
Abstract
A range of high specific activity accelerator-produced radionuclides in no-carrier-added (NCA) form, for uses in metabolic radiotherapy and for PET, has been investigated. To this aim it was necessary optimizing the irradiation parameters by determining the excitation functions of the nuclear reactions involved, as needed for the following selective radiochemical separations of the radionuclides of interest. For the NCA radionuclides investigated, the spectrometry measurements, done at LASA-INFN on gamma, X and on a spectra are discussed together with the measurements of radionuclidic, radiochemical and chemical purities by analytical and radioanalytical techniques.
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