Prosthetic joint infection (PJI) is a severe complication of arthroplasty and is still lacking diagnostic gold standards. PJI patients display high Toll-like receptor 2 (TLR2) serum levels, correlating with canonical inflammatory markers (C-reactive protein [CRP], interleukin 6 [IL-6], tumor necrosis factor alpha [TNF-α], and IL-1). Therefore, TLR2 serum levels could be considered a new potential diagnostic tool in the early detection of PJI. Copyright © 2014, American Society for Microbiology.
Toll-like receptor 2 in serum: a potential diagnostic marker of prosthetic joint infection? / E. Galliera, L. Drago, C. Vassena, C. Romanò, M.G. Marazzi, L. Salcito, M.M. Corsi Romanelli. - In: JOURNAL OF CLINICAL MICROBIOLOGY. - ISSN 0095-1137. - 52:2(2014 Feb), pp. 620-623. [10.1128/JCM.02727-13]
Toll-like receptor 2 in serum: a potential diagnostic marker of prosthetic joint infection?
E. Galliera
;L. DragoSecondo
;M.G. Marazzi;M.M. Corsi RomanelliUltimo
2014
Abstract
Prosthetic joint infection (PJI) is a severe complication of arthroplasty and is still lacking diagnostic gold standards. PJI patients display high Toll-like receptor 2 (TLR2) serum levels, correlating with canonical inflammatory markers (C-reactive protein [CRP], interleukin 6 [IL-6], tumor necrosis factor alpha [TNF-α], and IL-1). Therefore, TLR2 serum levels could be considered a new potential diagnostic tool in the early detection of PJI. Copyright © 2014, American Society for Microbiology.
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