Effect of mechanical, electrical and osmotic pressure on the phase transition properties and stability of phospholipid bilayers: Landau’s theory of one-component systems

A theoretical model has been developed to describe not only the temperature-induced phase transition of phospholipids bilayers but also the phase transitions induces by different types of pressure. The calculated pressure-temperature phase diagrams show that the first-order gel-liquid crystalline phase transition becomes a second-order one for dipalmitoylphosphatidylcholine / DPPC / bilayers at particular critical parameters.