The aim of this study was to investigate the effects of different species of Lactobacilli on hyphal formation and biofilm development by the opportunistic fungal pathogen Candida albicans. We employed 4 different Lactobacillus species, namely L. rhamnosus, L. acidophilus, L. plantarum and L. reuteri, and 2 C. albicans strains, the reference DAY286 and its isogenic hwp1/hwp1 mutant, the FJS24 strain. As assessed by morphological analysis and quantitative colorimetric assays, Lactobacillus crude filtrate supernatant fluids (CFSF) affected Candida, impairing both hyphal formation and biofilm production. The CFSF-mediated phenomenon occurred in a dilution- and time-dependent manner and was consistently observed, irrespective of the C. albicans HWP1 genotype.

Inhibitory effects of different lactobacilli on Candida albicans hyphal formation and biofilm development / C.F. Orsi, C. Sabia, A. Ardizzoni, B. Colombari, R.G. Neglia, S. Peppoloni, G. Morace, E. Blasi. - In: JOURNAL OF BIOLOGICAL REGULATORS & HOMEOSTATIC AGENTS. - ISSN 0393-974X. - 28:4(2014), pp. 743-752.

Inhibitory effects of different lactobacilli on Candida albicans hyphal formation and biofilm development

C.F. Orsi
Primo
;
G. Morace
Penultimo
;
2014

Abstract

The aim of this study was to investigate the effects of different species of Lactobacilli on hyphal formation and biofilm development by the opportunistic fungal pathogen Candida albicans. We employed 4 different Lactobacillus species, namely L. rhamnosus, L. acidophilus, L. plantarum and L. reuteri, and 2 C. albicans strains, the reference DAY286 and its isogenic hwp1/hwp1 mutant, the FJS24 strain. As assessed by morphological analysis and quantitative colorimetric assays, Lactobacillus crude filtrate supernatant fluids (CFSF) affected Candida, impairing both hyphal formation and biofilm production. The CFSF-mediated phenomenon occurred in a dilution- and time-dependent manner and was consistently observed, irrespective of the C. albicans HWP1 genotype.
No
English
Settore MED/07 - Microbiologia e Microbiologia Clinica
Articolo
Esperti anonimi
Ricerca di base
Pubblicazione scientifica
2014
28
4
743
752
10
Pubblicato
Periodico con rilevanza internazionale
pubmed
Aderisco
info:eu-repo/semantics/article
Inhibitory effects of different lactobacilli on Candida albicans hyphal formation and biofilm development / C.F. Orsi, C. Sabia, A. Ardizzoni, B. Colombari, R.G. Neglia, S. Peppoloni, G. Morace, E. Blasi. - In: JOURNAL OF BIOLOGICAL REGULATORS & HOMEOSTATIC AGENTS. - ISSN 0393-974X. - 28:4(2014), pp. 743-752.
none
Prodotti della ricerca::01 - Articolo su periodico
8
262
Article (author)
no
C.F. Orsi, C. Sabia, A. Ardizzoni, B. Colombari, R.G. Neglia, S. Peppoloni, G. Morace, E. Blasi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/263098
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