A young Down's syndrome patient developed tricuspid valve endocarditis several years after undergoing surgical closure of a congenital ventricular septal defect. Fungal etiology was established by PCR amplification of the Candida albicans ERG11 gene. Although antifungal therapy was administered, surgical replacement of the infected valve was required to eliminate the infection.
Candida albicans endocarditis diagnosed by PCR-based molecular assay in a critically ill pediatric patient / Brunella Posteraro, Piero Valentini, Angelica Delogu, Gabriella De Rosa, Simona Boccacci, Maurizio Sanguinetti, Aldo Nacci, Stefano Miceli Sopo, Orazio Ranno, Giulia Morace, Giovanni Fadda. - In: SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES. - ISSN 0036-5548. - 34:2(2002), pp. 145-147. [10.1080/00365540110077173]
Candida albicans endocarditis diagnosed by PCR-based molecular assay in a critically ill pediatric patient
G. Morace;
2002
Abstract
A young Down's syndrome patient developed tricuspid valve endocarditis several years after undergoing surgical closure of a congenital ventricular septal defect. Fungal etiology was established by PCR amplification of the Candida albicans ERG11 gene. Although antifungal therapy was administered, surgical replacement of the infected valve was required to eliminate the infection.
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