The reaction of enolates (2) of 1,3-dicarbonyl compounds with N-(2-bromomethylphenyl)benzenesulfonamides (1) gives N-phenylsulfonyl-2-hydroxy-1,2,3,4-tetrahydroquinoline derivatives (3) whose structure and stereochemistry were assigned on the basis of analytical and spectroscopic data. Some studies on the chemical behaviour of 3 are also reported.
Synthesis of 2-hydroxy-1,2,3,4-tetrahydroquinoline derivatives by a cyclocondensation reaction / G. Cremonesi, P. Dalla Croce, F. Fontana, C. La Rosa. - In: HETEROCYCLES. - ISSN 0385-5414. - 69:1(2006), pp. 475-480.
Synthesis of 2-hydroxy-1,2,3,4-tetrahydroquinoline derivatives by a cyclocondensation reaction
G. CremonesiPrimo
;P. Dalla CroceSecondo
;F. FontanaPenultimo
;C. La RosaUltimo
2006
Abstract
The reaction of enolates (2) of 1,3-dicarbonyl compounds with N-(2-bromomethylphenyl)benzenesulfonamides (1) gives N-phenylsulfonyl-2-hydroxy-1,2,3,4-tetrahydroquinoline derivatives (3) whose structure and stereochemistry were assigned on the basis of analytical and spectroscopic data. Some studies on the chemical behaviour of 3 are also reported.
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