Despite the widespread use of antifungals for prophylaxis, Candida bloodstream infection (BSI) remains the most frequent life-threatening fungal disease. From an analysis of multi-institutional surveys of Candida BSIs performed in Europe, including the large prospective survey by the European Confederation of Medical Mycology (2089 episodes from seven countries), a limited role of species with decreased susceptibility to azoles in causing BSIs and a low proportion of antifungal resistance was evident. Large prospective epidemiological surveys using common databases are needed to monitor trends in incidence and changes in species distribution, to identify new at-risk patients and to evaluate the impact of the introduction into the market of new antifungal agents.
|Titolo:||Candidaemia in Europe : epidemiology and resistance|
|Autori interni:||TORTORANO, ANNA MARIA (Primo)|
|Parole Chiave:||candida ; candidaemia ; antifungals ; resistance|
|Settore Scientifico Disciplinare:||Settore MED/42 - Igiene Generale e Applicata|
|Data di pubblicazione:||mag-2006|
|Digital Object Identifier (DOI):||10.1016/j.ijantimicag.2006.01.002|
|Appare nelle tipologie:||01 - Articolo su periodico|