To evaluate the bias and precision of the respiratory muscle training device formulas to predict respiratory minute volume (RMV) and volume of the reservoir bag (BV) on a cohort of subjects with Cystic Fibrosis (CF). CF patients with available pulmonary function tests and maximal voluntary manoeuvres were included in the study. Vital capacity and maximal voluntary ventilation were extracted from subjects’ records and then inserted to the manufacturer’s formulas to obtain RMV and BV (measured setting). RMV and BV were compared according to standard and measured formulas in males and females. Sample was described and then processed using Bland–Altman analysis. Bland–Altman analysis for RMV revealed a bias and precision of 8.8 ± 29 L/min in males and 28.8 ± 16 L/min in females; 0.4 ± 0.5 L in males and 0.7 ± 0.4 L in females for BV. Concordance correlation coefficients for RMV were −0.03 in males and 0.02 in females; 0.22 in males and 0.03 in females for BV, reinforcing an unsatisfactory concordance between measured and manufacturer setting. This study shows considerable discrepancies between the two methods, making the degree of agreement not clinically acceptable. This might cause inappropriate setting and disservice to patients with CF.

Isocapnic hyperpnea with a portable device in Cystic Fibrosis : an agreement study between two different set-up modalities / S. Gambazza, C. Ceruti, A. Brivio, G. Piaggi, S. Karapanagiotis, C. Colombo. - In: JOURNAL OF CLINICAL MONITORING AND COMPUTING. - ISSN 1387-1307. - 29:5(2015 Oct), pp. 569-572. [10.1007/s10877-014-9633-z]

Isocapnic hyperpnea with a portable device in Cystic Fibrosis : an agreement study between two different set-up modalities

S. Gambazza;C. Colombo
Ultimo
2015

Abstract

To evaluate the bias and precision of the respiratory muscle training device formulas to predict respiratory minute volume (RMV) and volume of the reservoir bag (BV) on a cohort of subjects with Cystic Fibrosis (CF). CF patients with available pulmonary function tests and maximal voluntary manoeuvres were included in the study. Vital capacity and maximal voluntary ventilation were extracted from subjects’ records and then inserted to the manufacturer’s formulas to obtain RMV and BV (measured setting). RMV and BV were compared according to standard and measured formulas in males and females. Sample was described and then processed using Bland–Altman analysis. Bland–Altman analysis for RMV revealed a bias and precision of 8.8 ± 29 L/min in males and 28.8 ± 16 L/min in females; 0.4 ± 0.5 L in males and 0.7 ± 0.4 L in females for BV. Concordance correlation coefficients for RMV were −0.03 in males and 0.02 in females; 0.22 in males and 0.03 in females for BV, reinforcing an unsatisfactory concordance between measured and manufacturer setting. This study shows considerable discrepancies between the two methods, making the degree of agreement not clinically acceptable. This might cause inappropriate setting and disservice to patients with CF.
cystic fibrosis; respiratory muscle training; spirometry
Settore MED/38 - Pediatria Generale e Specialistica
ott-2015
28-ott-2014
Article (author)
File in questo prodotto:
File Dimensione Formato  
art_10.1007_s10877-014-9633-z.pdf

accesso riservato

Tipologia: Publisher's version/PDF
Dimensione 850.99 kB
Formato Adobe PDF
850.99 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/250291
Citazioni
  • ???jsp.display-item.citation.pmc??? 0
  • Scopus 2
  • ???jsp.display-item.citation.isi??? 1
social impact