Tumor necrosis factor-alfa (TNF-α) is a cytokine that plays a central role in the pathogenesis of psoriasis; the treatment with anti–TNF-α agents, as etanercept, has proved to be highly effective although its mechanism on the overall epidermal cytoarchitecture has still to be elucidated. The aim of the present study was to investigate if etanercept treatment of psoriatic patients could affect the expression of the main biomarkers of keratinocyte terminal differentiation (TD) along with epithelial cell proliferation.
Anti-tumor necrosis factor-alfa and psoriasis : new insights on keratinocyte differentiation markers / F. Prignano, A. Gualerzi, E. Donetti, F. Ricceri, L. Tripo, L. Pescitelli, M. Bedoni. - In: JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY. - ISSN 0190-9622. - 68:4, supplement 1(2013), pp. AB193-AB193. ((Intervento presentato al 71. convegno Annual meeting of the American academy of dermatology (AAD) tenutosi a Miami Beach nel 2013.
|Titolo:||Anti-tumor necrosis factor-alfa and psoriasis : new insights on keratinocyte differentiation markers|
|Settore Scientifico Disciplinare:||Settore BIO/16 - Anatomia Umana|
|Data di pubblicazione:||2013|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1016/j.jaad.2012.12.797|
|Appare nelle tipologie:||01 - Articolo su periodico|