The definitive fate of peripherally injected PKH26 labelled bone marrow mononuclear cells expressing the CD34+ antigen following experimental myocardial cryodamage in rats(n=10)has been examined by direct visualization on photoconverted light and electron microscopy images. One week after injection in each rat of about 150,000CD34+ cells early stage PKH26+ vascular were localized in the infarcted areas, suggesting that a potential benefit of this therapeutic approach consists in the regeneration of the vasculature.

Direct visualization of neo-vessel formation following peripheral injection of bone marrow derived CD34+ cells in experimental myocardial damage / M.M. Ciulla, S. Ferrero, U. Gianelli, R. Paliotti, F. Magrini, P. Braidotti. - In: MICRON. - ISSN 0968-4328. - 38:3(2007), pp. 321-322. [10.1016/j.micron.2006.08.007]

Direct visualization of neo-vessel formation following peripheral injection of bone marrow derived CD34+ cells in experimental myocardial damage

M.M. Ciulla
Primo
;
S. Ferrero
Secondo
;
U. Gianelli;R. Paliotti;F. Magrini
Penultimo
;
P. Braidotti
Ultimo
2007

Abstract

The definitive fate of peripherally injected PKH26 labelled bone marrow mononuclear cells expressing the CD34+ antigen following experimental myocardial cryodamage in rats(n=10)has been examined by direct visualization on photoconverted light and electron microscopy images. One week after injection in each rat of about 150,000CD34+ cells early stage PKH26+ vascular were localized in the infarcted areas, suggesting that a potential benefit of this therapeutic approach consists in the regeneration of the vasculature.
English
myocardial cryoinjury ; bone marrow monuclear cells ; angiogenesis ; electron microscopy ; photoconversion
Settore MED/09 - Medicina Interna
Settore MED/08 - Anatomia Patologica
Articolo
Sì, ma tipo non specificato
2007
Elsevier
38
3
321
322
Periodico con rilevanza internazionale
info:eu-repo/semantics/article
Direct visualization of neo-vessel formation following peripheral injection of bone marrow derived CD34+ cells in experimental myocardial damage / M.M. Ciulla, S. Ferrero, U. Gianelli, R. Paliotti, F. Magrini, P. Braidotti. - In: MICRON. - ISSN 0968-4328. - 38:3(2007), pp. 321-322. [10.1016/j.micron.2006.08.007]
none
Prodotti della ricerca::01 - Articolo su periodico
6
262
Article (author)
Periodico con Impact Factor
M.M. Ciulla, S. Ferrero, U. Gianelli, R. Paliotti, F. Magrini, P. Braidotti
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/24205
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