Although parkinsonism is considered a core feature of dementia with Lewy bodies (DLB), it is occasionally mild or even absent. I-FP-CIT SPECT has been accepted as a diagnostic support tool in this context, given that low striatal uptake is associated with neuronal loss. The aim of this retrospective study was to look for correlations between I-FP-CIT uptake in the striatum and clinical extrapyramidal signs (EPSs) in patients with a diagnosis of probable DLB to clarify the extent to which the supporting role of I-FP-CIT is related to motor impairment.
|Titolo:||Correlation Between 123I-FP-CIT Brain SPECT and Parkinsonism in Dementia With Lewy Bodies : Caveat for Clinical Use|
|Settore Scientifico Disciplinare:||Settore MED/36 - Diagnostica per Immagini e Radioterapia|
|Data di pubblicazione:||gen-2015|
|Digital Object Identifier (DOI):||10.1097/RLU.0000000000000602|
|Appare nelle tipologie:||01 - Articolo su periodico|
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|Del Sole et al. - 2015 - Correlation between 123I-FP-CIT brain SPECT and parkinsonism in dementia with Lewy bodies caveat for clinical u.pdf||Publisher's version/PDF||Administrator Richiedi una copia|