The synthesis of multifunctional organic catalysts, easily obtained by the condensation of (S)-proline with 1,1'-binaphthyl-2,2'-diamine is reported. These C-2 as well as C, symmetric prolinamides were shown to be able to promote the direct aldol condensation between acetone, methoxyacetone or cyclohexanone and different aldehydes in very good yields and high enantio selectivities.
A multifunctional proline-based organic catalyst for enantioselective aldol reactions / S. Guizzetti, M. Benaglia, L. Pignataro, A. Puglisi. - In: TETRAHEDRON-ASYMMETRY. - ISSN 0957-4166. - 17:19(2006), pp. 2754-2760. [10.1016/j.tetasy.2006.10.018]
A multifunctional proline-based organic catalyst for enantioselective aldol reactions
S. GuizzettiPrimo
;M. Benaglia
;L. PignataroPenultimo
;A. PuglisiUltimo
2006
Abstract
The synthesis of multifunctional organic catalysts, easily obtained by the condensation of (S)-proline with 1,1'-binaphthyl-2,2'-diamine is reported. These C-2 as well as C, symmetric prolinamides were shown to be able to promote the direct aldol condensation between acetone, methoxyacetone or cyclohexanone and different aldehydes in very good yields and high enantio selectivities.
| File | Dimensione | Formato | |
|---|---|---|---|
|
TetAs_2006_2754.pdf
accesso riservato
Tipologia:
Publisher's version/PDF
Dimensione
165.59 kB
Formato
Adobe PDF
|
165.59 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
