In this study, cytogenetic analysis of an infertile mare revealed a 64, XY karyotype. The XY sex-reversed animal had a female phenotype with gonadal dysgenesis. Using Southern blot analysis, we tested for the presence of two Y-specific genes SRY and ZFY by using DNA isolated from peripheral blood leukocytes. The results showed that at least the DNA-binding domain of the SRY gene was deleted from the Y chromosome of the XY mare but that the ZFY gene was present on this chromosome.
|Titolo:||Molecular analysis of a XY mare with gonadal dysgenesis|
PARMA, PIETRO (Penultimo)
|Data di pubblicazione:||1995|
|Digital Object Identifier (DOI):||10.1111/j.1601-5223.1995.00109.x|
|Appare nelle tipologie:||01 - Articolo su periodico|