We report two neonates with human parechoviruses type 3 (HPeV3) encephalitis. Both newborns presented with fever, irritability, and seizures. Cerebrospinal fluid (CSF) analyses were normal, but magnetic resonance imaging revealed white matter damage, suggesting HPeV infection. HPeV3-RNA was detected in CSF samples and in blood, stool, urine and respiratory samples, indicating the dissemination of the virus.
Two cases of neonatal human parechovirus 3 encephalitis / E. Pariani, L. Pellegrinelli, L. Pugni, P. Bini, S. Perniciaro, L. Bubba, V. Primache, A. Amendola, M. Barbarini, F. Mosca, S. Binda. - In: THE PEDIATRIC INFECTIOUS DISEASE JOURNAL. - ISSN 0891-3668. - 33:11(2014 May 21), pp. 1191-1193. [Epub ahead of print] [10.1097/INF.0000000000000412]
Two cases of neonatal human parechovirus 3 encephalitis
E. ParianiPrimo
;L. PellegrinelliSecondo
;L. Pugni;S. Perniciaro;L. Bubba;V. Primache;A. Amendola;F. MoscaPenultimo
;S. BindaUltimo
2014
Abstract
We report two neonates with human parechoviruses type 3 (HPeV3) encephalitis. Both newborns presented with fever, irritability, and seizures. Cerebrospinal fluid (CSF) analyses were normal, but magnetic resonance imaging revealed white matter damage, suggesting HPeV infection. HPeV3-RNA was detected in CSF samples and in blood, stool, urine and respiratory samples, indicating the dissemination of the virus.
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