Mammary epithelial cell identity depends on a set of genes epigenetically-regulated by maintenance proteins, the best-characterized of which belong to the Trithorax and Polycomb groups. Perturbations in expression of these proteins may disrupt cell identity and trigger tumor initiation.

Cell identity disruption in breast cancer precursors / D. Coradini, P. Boracchi, S. Oriana, E. Biganzoli, F. Ambrogi. - In: ANTICANCER RESEARCH. - ISSN 0250-7005. - 34:3(2014 Mar), pp. 1307-1319.

Cell identity disruption in breast cancer precursors

P. Boracchi
Secondo
;
E. Biganzoli
Penultimo
;
F. Ambrogi
Ultimo
2014

Abstract

Mammary epithelial cell identity depends on a set of genes epigenetically-regulated by maintenance proteins, the best-characterized of which belong to the Trithorax and Polycomb groups. Perturbations in expression of these proteins may disrupt cell identity and trigger tumor initiation.
Atypical ductal hyperplasia; Cell identity; Ductal carcinoma in situ; Mammary epithelium
Settore MED/01 - Statistica Medica
Settore MED/06 - Oncologia Medica
mar-2014
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/238383
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