Opsoclonus-myoclonus syndrome (OMS) is characterized by opsoclonus and arrhythmic-action myoclonus that predominantly involves the trunk, limbs, and head. Human herpes virus-6 (HHV-6) can rarely cause encephalitis in immunocompetent children and adults. Here we report on a case of OMS associated with HHV-6 rhomboencephalitis. HHV-6 infection should be considered in OMS adults and detection of cell-free viral DNA, indicative of active infection, is mandatory in such cases.
Opsoclonus-myoclonus syndrome associated with human herpes virus-6 rhomboencephalitis / V. Belcastro, M. Piola, S. Binda, D. Santoro, M. Rezzonico, M. Arnaboldi. - In: JOURNAL OF THE NEUROLOGICAL SCIENCES. - ISSN 0022-510X. - 341:1-2(2014), pp. 165-166. [10.1016/j.jns.2014.04.013]
Opsoclonus-myoclonus syndrome associated with human herpes virus-6 rhomboencephalitis
M. PiolaSecondo
;S. Binda;D. Santoro;
2014
Abstract
Opsoclonus-myoclonus syndrome (OMS) is characterized by opsoclonus and arrhythmic-action myoclonus that predominantly involves the trunk, limbs, and head. Human herpes virus-6 (HHV-6) can rarely cause encephalitis in immunocompetent children and adults. Here we report on a case of OMS associated with HHV-6 rhomboencephalitis. HHV-6 infection should be considered in OMS adults and detection of cell-free viral DNA, indicative of active infection, is mandatory in such cases.
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