Background: Increasing aortic diameter is thought to be an important risk factor for acute type B aortic dissection (ABAD). However, some patients develop ABAD in the absence of aortic dilatation. In this report, we sought to characterize ABAD patients who presented with a descending thoracic aortic diameter <3.5 cm. Methods: We categorized 613 ABAD patients enrolled in the International Registry of Acute Aortic Dissection from 1996 to 2009 according to the aortic diameter <3.5 cm (group 1) and <3.5 cm (group 2). Demographics, clinical presentation, management, and outcomes of the two groups were compared. Results: Overall, 21.2% (n = 130) had an aortic diameter <3.5 cm. Patients in group 1 were younger (60.5 vs 64.0 years; P =.015) and more frequently female (50.8% vs 28.6%; P <.001). They presented more often with diabetes (10.9% vs 5.9%; P =.050), history of catheterization (17.0% vs 6.7%; P =.001), and coronary artery bypass grafting (9.7% vs 3.4%; P =.004). Marfan syndrome was equally distributed in the two groups. The overall in-hospital mortality did not differ between groups 1 and 2 (7.6% vs 10.1%; P =.39). Conclusions: About one-fifth of patients with ABAD do not present with any aortic dilatation. These patients are more frequently females and younger, when compared with patients with aortic dilatation. This report is an initial investigation to clinically characterize this cohort, and further research is needed to identify risk factors for aortic dissection in the absence of aortic dilatation.

Acute type B aortic dissection in the absence of aortic dilatation / S. Trimarchi, F.H.W. Jonker, J.B. Froehlich, G.R. Upchurch, F.L. Moll, B.E. Muhs, V. Rampoldi, H.J. Patel, K.A. Eagle, Iternational Registry of Acute Aortic Dissection (IRAD) investigators. - In: JOURNAL OF VASCULAR SURGERY. - ISSN 0741-5214. - 56:2(2012 Aug), pp. 311-316. [10.1016/j.jvs.2012.01.055]

Acute type B aortic dissection in the absence of aortic dilatation

S. Trimarchi;V. Rampoldi;
2012-08

Abstract

Background: Increasing aortic diameter is thought to be an important risk factor for acute type B aortic dissection (ABAD). However, some patients develop ABAD in the absence of aortic dilatation. In this report, we sought to characterize ABAD patients who presented with a descending thoracic aortic diameter <3.5 cm. Methods: We categorized 613 ABAD patients enrolled in the International Registry of Acute Aortic Dissection from 1996 to 2009 according to the aortic diameter <3.5 cm (group 1) and <3.5 cm (group 2). Demographics, clinical presentation, management, and outcomes of the two groups were compared. Results: Overall, 21.2% (n = 130) had an aortic diameter <3.5 cm. Patients in group 1 were younger (60.5 vs 64.0 years; P =.015) and more frequently female (50.8% vs 28.6%; P <.001). They presented more often with diabetes (10.9% vs 5.9%; P =.050), history of catheterization (17.0% vs 6.7%; P =.001), and coronary artery bypass grafting (9.7% vs 3.4%; P =.004). Marfan syndrome was equally distributed in the two groups. The overall in-hospital mortality did not differ between groups 1 and 2 (7.6% vs 10.1%; P =.39). Conclusions: About one-fifth of patients with ABAD do not present with any aortic dilatation. These patients are more frequently females and younger, when compared with patients with aortic dilatation. This report is an initial investigation to clinically characterize this cohort, and further research is needed to identify risk factors for aortic dissection in the absence of aortic dilatation.
Settore MED/22 - Chirurgia Vascolare
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/234035
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