Skeletal myogenesis has been and is currently under extensive study in both mammals and teleosts, with the latter providing a good model for skeletal myogenesis because of their flexible and conserved genome. Parallel investigations of muscle studies using both these models have strongly accelerated the advances in the field. However, when transferring the knowledge from one model to the other, it is important to take into account both their similarities and differences. The main difficulties in comparing mammals and teleosts arise from their different temporal development. Conserved aspects can be seen for muscle developmental origin and segmentation, and for the presence of multiple myogenic waves. Among the divergences, many fish have an indeterminate growth capacity throughout their entire life span, which is absent in mammals, thus implying different post-natal growth mechanisms. This review covers the current state of the art on myogenesis, with a focus on the most conserved and divergent aspects between mammals and teleosts.

Comparative myogenesis in teleosts and mammals / G. Rossi, G. Messina. - In: CELLULAR AND MOLECULAR LIFE SCIENCES. - ISSN 1420-682X. - 71:16(2014), pp. 3081-3099. [10.1007/s00018-014-1604-5]

Comparative myogenesis in teleosts and mammals

G. Rossi
Primo
;
G. Messina
Ultimo
2014

Abstract

Skeletal myogenesis has been and is currently under extensive study in both mammals and teleosts, with the latter providing a good model for skeletal myogenesis because of their flexible and conserved genome. Parallel investigations of muscle studies using both these models have strongly accelerated the advances in the field. However, when transferring the knowledge from one model to the other, it is important to take into account both their similarities and differences. The main difficulties in comparing mammals and teleosts arise from their different temporal development. Conserved aspects can be seen for muscle developmental origin and segmentation, and for the presence of multiple myogenic waves. Among the divergences, many fish have an indeterminate growth capacity throughout their entire life span, which is absent in mammals, thus implying different post-natal growth mechanisms. This review covers the current state of the art on myogenesis, with a focus on the most conserved and divergent aspects between mammals and teleosts.
Mouse and zebrafish; Muscle fiber types; Myotome and dermomyotome; Primary and secondary myogenesis; Regeneration; Satellite cells
Settore BIO/17 - Istologia
   Role of the transcription factor Nfix in muscle regeneration and muscular dystrophies (RegeneratioNfix)
   RegeneratioNfix
   EUROPEAN COMMISSION
   FP7
   280611
2014
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/233800
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