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Melanoma is one of the most aggressive tumors. Once melanoma becomes metastatic, current therapeutic strategies usually fail. In this chapter, we discuss the idea of using cancer stem cells as target. The identification of suitable biomarkers appears to be a crucial step in this direction. A multidisciplinary approach based on mathematical models can help overcome the limitations of traditional biological methods

Cancer stem cells in melanoma:biomarkers and mathematical models / S. Zapperi, C. La Porta - In: Cancer Stem Cells / [a cura di] V.K. Rajasekhar. - [s.l] : Wiley Press, 2014 Mar. - ISBN 9781118356166. - pp. 133-143 [10.1002/9781118356203.ch10]

Cancer stem cells in melanoma:biomarkers and mathematical models

S. Zapperi;C. La Porta
2014-03

Abstract

Melanoma is one of the most aggressive tumors. Once melanoma becomes metastatic, current therapeutic strategies usually fail. In this chapter, we discuss the idea of using cancer stem cells as target. The identification of suitable biomarkers appears to be a crucial step in this direction. A multidisciplinary approach based on mathematical models can help overcome the limitations of traditional biological methods
Biomarkers; BRAF; Cancer stem cells (CSCs); Mathematical models; Melanoma
Settore MED/04 - Patologia Generale
Book Part (author)
03 - Contributo in volume
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/233763
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