Melanoma is one of the most aggressive tumors. Once melanoma becomes metastatic, current therapeutic strategies usually fail. In this chapter, we discuss the idea of using cancer stem cells as target. The identification of suitable biomarkers appears to be a crucial step in this direction. A multidisciplinary approach based on mathematical models can help overcome the limitations of traditional biological methods
Cancer stem cells in melanoma:biomarkers and mathematical models / S. Zapperi, C. La Porta - In: Cancer Stem Cells / [a cura di] V.K. Rajasekhar. - [s.l] : Wiley Press, 2014 Mar. - ISBN 9781118356166. - pp. 133-143
Titolo: | Cancer stem cells in melanoma:biomarkers and mathematical models |
Autori: | |
Parole Chiave: | Biomarkers; BRAF; Cancer stem cells (CSCs); Mathematical models; Melanoma |
Settore Scientifico Disciplinare: | Settore MED/04 - Patologia Generale |
Data di pubblicazione: | mar-2014 |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1002/9781118356203.ch10 |
Tipologia: | Book Part (author) |
Appare nelle tipologie: | 03 - Contributo in volume |