Objective: To evaluate whether the presence of endometriomas affects ovarian function. Design: Prospective cohort study. Setting: Infertility unit of an academic setting. Patient(s): Twenty-nine women undergoing an IVF cycle. Intervention(s): Prospective evaluation of women with unoperated unilateral endometriomas undergoing IVF. The affected and contralateral intact gonads were compared in terms of responsiveness and oocyte quality. Main Outcome Measure(s): Oocyte developmental competence. Results: Ovarian responsiveness and oocyte quality did not significantly differ between the affected and intact gonads. The number of codominant follicles, the number of oocytes retrieved, and the number of suitable oocytes in affected and intact gonads were 3.7 ± 2.4 and 4.1 ± 1.7, 4.2 ± 3.1 and 4.7 ± 2.5, and 3.1 ± 2.6 and 3.5 ± 2.3, respectively. The number of viable embryos and the number of high-quality embryos were 1.8 ± 2.1 and 1.8 ± 1.4 and 1.0 ± 1.7 and 0.8 ± 0.7, respectively. The fertilization rate in the affected and intact gonads was 64% and 64%, respectively. The cleavage rate was 58% and 51%, respectively. The rate of high-quality embryos was 31% and 21%, respectively. Conclusion(s): In women undergoing IVF, the presence of ovarian endometriomas does not affect oocyte developmental competence.
Ovarian endometriomas and oocyte quality : insights from in vitro fertilization cycles / F. Filippi, L. Benaglia, A. Paffoni, L. Restelli, P. Vercellini, E. Somigliana, L. Fedele. - In: FERTILITY AND STERILITY. - ISSN 0015-0282. - 101:4(2014 Apr), pp. 988-993.e1.
|Titolo:||Ovarian endometriomas and oocyte quality : insights from in vitro fertilization cycles|
BENAGLIA, LAURA (Secondo)
FEDELE, LUIGI (Ultimo)
|Parole Chiave:||Endometrioma ; IVF ; oocyte|
|Settore Scientifico Disciplinare:||Settore MED/40 - Ginecologia e Ostetricia|
|Data di pubblicazione:||apr-2014|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1016/j.fertnstert.2014.01.008|
|Appare nelle tipologie:||01 - Articolo su periodico|